- The National Science Foundation recently granted the University of Illinois $3 million for an interdisciplinary graduate student training program to help form new insight on the brain—and to expand participation in the field of brain science itself.
- Massive Simulation of the HIV ‘Shell’ Reveals New Vulnerabilities that We Might Exploit to Eliminate the VirusIt took two years, two supercomputers and two Illinois researchers, Juan Perilla and the late Klaus Schulten, to simulate 1.2 microseconds in the life of an HIV capsid, a protein cage that protects the viral genome.
- Lydia Kisley, a Beckman-Brown Interdisciplinary Postdoctoral Fellow, and colleagues including Martin Grueble and Deborah Leckband, recently used Fast Relaxation Imaging (FReI) to investigate the folding stability and dynamics of proteins within polyacrylamide hydrogels.
- Martin Burke's Research Team Demonstrated that a Small Molecule Can Transport Iron in Human Cells and Live AnimalsMartin Burke's research team has demonstrated that a small molecule can transport iron in human cells and live animals when proteins that normally do the same job are missing, a condition that often causes severe anemia in patients.
- Paul Hergenrother's team reports that they now know how to build a molecular Trojan horse that can penetrate gram-negative bacteria, solving a problem that for decades has stalled the development of effective new antibiotics against these increasingly drug-resistant microbes.
- Martin Burke Proposes Billion-Dollar Project to Synthesize Most of the Known Organic Natural Products
Martin Burke proposes billion-dollar project to synthesize most of the hundreds of thousands of known organic natural products in search of new medicines.
- Douglas Mitchell's research group has created a new bioinformatics tool, RODEO, that promises to capture the breadth of microbial biosynthetic potential.
- The research of the chemistry department is highlighted in this LAS News Article.
- Fuel cells have long held promise as power sources, but low efficiency has created obstacles to realizing that promise. Researchers at the University of Illinois and collaborators have identified the active form of an iron-containing catalyst for the trickiest part of the process: reducing oxygen gas, which has two oxygen atoms, so that it can break apart and combine with ionized hydrogen to make water. The finding could help researchers refine better catalysts, making fuel cells a more energy- and cost-efficient option for powering vehicles and other applications.
Illinois professors Nancy Sottos and Andrew Gerwith developed a method to comprehensively measure the mechanical stress and strain in lithium-ion batteries.
- Chemists led by University of Illinois professor M. Christina White and graduate student Thomas Osberger found that two small-molecule iron catalysts can oxidize chiral amino acids and peptides to an array of unnatural forms, giving researchers more options for developing drug candidates.
- Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline.
Suslick's sensors monitored pollutant exposure of Disney original artwork, like this 1928 'Steamboat Willie' celluloid, during a trip to China © Disney Enterprises, Inc., Courtesy of Walt Disney An
Members of the laboratory of Prof. Scott Silverman have identified synthetic DNA enzymes that cleave amide bonds, which are fundamental components of proteins.
- A new class of small, thin electronic sensors can monitor temperature and pressure within the skull – crucial health parameters after a brain injury or surgery – then melt away when they are no longer needed, eliminating the need for additional surgery to remove the monitors and reducing the risk of infection and hemorrhage.