The 27th Annual Beak-Pines Organic Area 
ALLERTON CONFERENCE

Sponsored by
Dr. Seemon H. Pines, Prof. Peter and Mrs. Beak, and Merck & Co.

Allerton Park, Saturday, November 9, 2013

Conference Schedule

8:00 a.m.

Check-in/Continental Breakfast
Session I: Shauna Paradine, Chair
8:40 a.m.

Opening Remarks
9:00 a.m.

Alex Cioffi (Prof. Martin D. Burke)
Restoration of cell growth with small molecule surrogates for missing proteins
9:20 a.m.

Josh Kaitz (Prof. Jeffrey S. Moore)
Discovery of a reversible, catioinc macrocyclization mechanism and control of cyclic copolymer microstructure by homopolymer scrambling
9:40 a.m.

Norio Yasui (Prof. John A. Katzenellenbogen)
A Bead-Supported Kit-Like Preparation of [18F]SiFB (([18F]-di(t-butyl)silyl)benzoic Acid N-hydroxylsuccinimidyl Ester) and Its Derivatives Greatly Simplifies Radiolabeling and Purification of PET Imaging Agents
10:00 a.m.

Poster Session I
Break for poster session in Gallery with snacks/coffee
Talks will resume in library at 10:50 am
10:50 a.m.

Joel Melby (Prof. Douglas A. Mitchell)
Understanding the Complex Orchestration of Enzymatic Processing Thiazole/Oxazole-Modified Microcins
11:10 a.m.

Iulia Stambeanu (Prof. M. Christina White)
Catalyst-Controlled C-O versus C-N Allylic Functionaliztion of Terminal Olefins
11:30 a.m.

Lien Nguyen (Prof. Steven C. Zimmerman)
Bis-amidinium based ligands as potential therapeutics for DM
11:50 a.m.

Lunch in the Main Dining Room
Tables will be assigned to each person previously. Tables will be seated and called to go through buffet
Session II:

Hannah Haley, Chair
1:20 p.m.

Dr. Robert Stavenger, GlaxoSmithKline
Drug Discovery, Collaboration, and Partnership
2:00 p.m.

Michael Lambrecht (Prof. Paul Hergenrother)
Chemical Investigations of Poly(ADP-Ribose
2:20 p.m.

Spencer Peck (Prof. Wilfred A. van der Donk)
Cold Iron: Trapping an Intermediate in Hydroxyethylphosphonate Dioxygenase Catalysis
2:40 p.m. Poster Session II
Poster session and snacks in the Gallery. Talks resume in the library at 3:10 p.m.
3:30 p.m.

Andrew Ickes (Prof. Kami L. Hull)
Rhodium-Catalyzed, Chemo- and Regioselective Markovnikov Hydroamination of Allylimines
3:50 p.m.

Benjamin Brandsen (Prof. Scott K. Silverman)
DNA-Catalyzed Hydrolysis of Esters and Aromatic Amides
4:10 p.m. Lindsey Cullen (Prof. Scott E. Denmark)

Catalytic Conjugate Addition of Acyl Anion Equivalents Promoted by Fluorodesilylation
4:30 p.m. Break
4:50 p.m. Closing Remarks and Presentation of the Seemon H. Pines Award

The annual Beak-Pines Organic Area Allerton Conference is held at beautiful Allerton Park, an English-style estate located approximately 20 miles southwest of Champaign. At this conference one student from each organic chemistry research group presents his/her work in the old library of the Robert Allerton House. Two more students from each group present their work in the form of a poster. Lunch is enjoyed in the grand dining hall, and after lunch free time is used to wander through the more then 5,000 acres of forest and prairie along the Sangamon River. The park features formal English gardens and over 100 outdoor sculptures. At the end of the day, the Seemon Pines award is given to the most outstanding presentation.