Contact Information
University of Illinois
600 S Mathews Ave
208 RAL, MC-712
Urbana, IL 61801
Additional Campus Affiliations
Associate Professor, Chemical and Biomolecular Engineering
Director of Graduate Studies, Chemical and Biomolecular Engineering
Associate Professor, Micro and Nanotechnology Lab
Co-Chair, Institutional Biosafety Committee, Office of the Vice Chancellor for Research and Innovation
Chien Family Professorial Scholar, Chemical and Biomolecular Engineering
Biography
Associate Professor Department of Chemical & Biomolecular Engineering
Affiliate in the Department of Chemistry
Affiliate in the Center for Biophysics and Computational Biology
Research Description
The Kraft group combines engineering principles and cutting-edge imaging technologies to overcome barriers to progress in biomedical research. We focus on identifying, and exploiting the relationship between cell composition and biological function. A key aspect of our research is the combination of computational statistics with chemical imaging techniques for quantitative single cell analysis with location specificity. We are using our new tools to solve problems in a broad range of biomedical research areas. This includes applied research in directing stem cell differentiation for tissue engineering and the design of efficient drug delivery vehicles. We also perform basic research on influenza virus replication.
Recent Publications
Pastrana-Otero, I., Majumdar, S., Gilchrist, A. E., Harley, B. A. C., & Kraft, M. L. (2022). Identification of the Differentiation Stages of Living Cells from the Six Most Immature Murine Hematopoietic Cell Populations by Multivariate Analysis of Single-Cell Raman Spectra. Analytical Chemistry, 94(35), 11999-12007. https://doi.org/10.1021/acs.analchem.2c00714
Gorman, B. L., Brunet, M. A., & Kraft, M. L. (2021). Depth correction of 3D NanoSIMS images using secondary electron pixel intensities. Biointerphases, 16(4), 1ENG. [041005]. https://doi.org/10.1116/6.0001092
Gorman, B. L., & Kraft, M. L. (2020). High-Resolution Secondary Ion Mass Spectrometry Analysis of Cell Membranes. Analytical Chemistry, 92(2), 1645-1652. https://doi.org/10.1021/acs.analchem.9b04492
Gorman, B. L., Brunet, M. A., Pham, S. N., Kraft, M. L., Kraft, M. L., & Kraft, M. L. (2020). Measurement of Absolute Concentration at the Subcellular Scale. ACS Nano, 14(6), 6414-6419. https://doi.org/10.1021/acsnano.0c04285
Kraft, M., Anderton, C., & Weber, P. (2020). Correlated Imaging of Topology and Composition within Phase-separated Supported Lipid Membranes. Microscopy and Microanalysis, 26(S2), 1602-1603. [623]. https://doi.org/10.1017/S143192762001867X