THE 28TH ANNUAL BEAK-PINES ORGANIC AREA 
ALLERTON CONFERENCE

Sponsored by
Dr. Seemon H. Pines, Prof. Peter and Mrs. Beak, and Merck & Co.  
Allerton Park, Saturday, November 8, 2014

 

8:00AM CHECK-IN/CONTINENTAL BREAKFAST

SESSION I:

 GREGORY KORTMAN, CHAIR
8:40AM OPENING REMARKS
9:00AM

Anthony Grillo (Prof. Martin D. Burke)
Restoring Physiology in Protein Deficient Cells with Small Molecules
9:20AM

Jun Li (Prof. Jeffrey S. Moore)
Mechanophore Activation at Hetero-interfaces
9:40AM Subha Mukherjee (Prof. Wilfred A. van der Donk)
Mechanistic Studies on the Substrate-tolerant Lanthipeptide Synthetase ProcM
10:00AM

POSTER SESSION I
Break for poster session in the Gallery with snacks and coffee
Talks will resume in the library at 10:50AM
10:50AM

Robert Hicklin (Prof. Paul J. Hergenrother)
Stereochemically Complex and Structurally Diverse Small Molecules from Pleuromutilin: Synthesis, Structural Evaluation, and Biological Activity
11:10AM

Stephen Ammann (Prof. M. Christina White)
Terminal Olefins to Chromans, Isochromans, and Pyrans via Allylic C–H Oxidation
11:30AM

Caitlin Deane (Prof. Douglas A. Mitchell)
Biosynthetic Engineering of Unnatural Natural Products
11:50AM

LUNCH IN MAIN DINING ROOM - GROUP I
Tables will be assigned to each person previously. Tables will be seated and called to go through the buffet
12:40AM

LUNCH IN MAIN DINING ROOM - GROUP II
Tables will be assigned to each person previously. Tables will be seated and called to go through the buffet 
SESSION II: BRANDON BURKHART, CHAIR
1:40PM

Dr. Kevin G. Pinney (Baylor University)
Small-Molecule, Tubulin Binding, Vascular Disrupting Agents as Anti-Cancer Therapeutics
2:20PM

Hyung Min Chi (Prof. Scott E. Denmark)
Catalytic, Enantioselective, Intramolecular Carbosulfenylation of Olefins. Mechanistic Aspects: A Remarkable Case of Negative Catalysis
2:40PM

Chih-Chi Chu (Prof. Scott K. Silverman)
DNA-Catalyzed Conjugation of Nucleic Acids and Tyrosine Side Chain

 

3:00PM

POSTER SESSION II
Break for poster session in the Gallery with snacks and coffee
Talks will resume in the library at 3:50PM

3:50PM

Seth Ensign (Prof. Kami L. Hull)
Rhodium-Mediated Substrate Controlled Markovnikov and Anti-Markovnikov Hydroamination

4:10PM

Yugang Bai (Prof. Steven C. Zimmerman)
Drug-functionalized Cell-penetrating Peptides for Enhanced Delivery and Binding in Myotonic Dystrophy Type 1 Treatment
4:30PM BREAK
4:50PM CLOSING REMARKS AND PRESENTATION OF SEEMON PINES AWARD