Researchers including Professor Chad Rienstra are the first to describe in atomic detail a chemical interaction that is vital to blood clotting-- an interaction that has baffled scientists for decades.
The researchers combined laboratory detective work with supercomputer simulations and solid-state nuclear magnetic resonance (SSNMR) to get at the problem from every angle. They also made use of tiny rafts of lipid membranes called nanodiscs, using an approach developed at Illinois by biochemistry professor Stephen Sligar.
The study appears online in the Journal of Biological Chemistry.
For more the complete University of Illiniois News Bureau article on the study, please click here.