Professor Scott Denmark, the Reynold C. Fuson Professor of Chemistry, received the Eros Best Reagent Award for the reagent N,N'-Bis[(11bR)-3,5-dihydro-3,5-dimethyl-4-oxido-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]diazaphosphepin-4-yl]-N,N'-dimethyl-1,5-pentanediamine. The award was created to honor the work of the authors to the online edition of Encyclopedia of Reagents for Organic Synthesis and is sponsored by Aldrich® Chemistry and John Wiley & Sons.
Denmark has pioneered the concept of chiral Lewis base activation of Lewis acids for catalysis in main group synthetic organic chemistry. His group has also developed palladium-catalyzed cross-couplings with organofunctional silicon compounds.
The bis (phosphoramide) reagent, originally discovered in 2001, has been widely used as a chiral catalyst in Lewis base-catalyzed enantioselective carbonyl addition reactions.
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