St. Elmo Brady's Postdoctoral Inclusive Excellence Symposium features two postdoctoral speakers

Date

05/20/21

The St. Elmo Brady's Postdoctoral Inclusive Excellence Symposium will feature two “rising star” postdoctoral researchers, Ivan A. Moreno-Hernandez and Melanie R. McReynolds, in virtual presentations on June 4 and June 11.

Ivan A. Moreno-Hernandez has been a postdoctoral fellow with Prof. A. Paul Alivisatos at the University of California, Berkeley, since 2019 and has worked on understanding and controlling the reactive chemical environment created during liquid cell electron microscopy experiments. Moreno-Hernandez will deliver a virtual presentation on Jun 4, 2021, at 1 p.m. Central Time. Register here.

Melanie R. McReynolds is a Howard Hughes Medical Institute Hanna H. Gray postdoctoral fellow and Burroughs Wellcome Fund Postdoctoral Enrichment Program awardee at Princeton University, where her research focuses on the intersection of metabolic decline and aging. McReynolds will present virtually on June 11, 2021, at 1 p.m. Central Time. Register here.

In recognizing the importance of sustainable diversity and inclusion and the competitive advantage it gives our Illinois Chemistry community, the department created the St. Elmo Brady Postdoctoral Inclusive Excellence seminar series in 2020. The initiative invites talented underrepresented postdocs of color currently conducting postdoctoral research at top chemistry programs across the country to present their research to the students and faculty at Illinois Chemistry.

Ivan A. Moreno-Hernandez

Ivan received a Bachelor of Science degree with University Honors in chemistry and physics from the University of Nebraska-Lincoln. Ivan continued his studies in chemistry as an NSF Graduate Research Fellow with Prof. Nathan Lewis at the California Institute of Technology, completing his PhD in 2019. Ivan focused on the study of semiconductor/metal-oxide heterojunctions for photoelectrochemical applications and on the discovery of earth-abundant electrocatalysts for anodic reactions in acidic electrolytes.

Symposium title: Addressing renewable energy challenges through
electrocatalyst discovery and in-situ nanoscale observations

Electrochemical technologies can couple renewable energy sources with our chemical infrastructure, thereby enabling sustainable energy practices. The implementation of these technologies will rely on both the discovery of new electrochemical materials with improved performance and the development of techniques to understand complex reaction dynamics at the nanoscale. We will first discuss the discovery of an earth-abundant class of electrocatalysts, crystalline transition metal antimonates, that are thermodynamically stable for anodic reactions in acidic electrolytes. Our discussion will then focus on the development of redox-mediated liquid cell electron microscopy, a technique that allows electrochemical reactions to be observed in real time at near-atomic resolution.

Melanie R. McReynolds

Melanie holds a Bachelor of Science degree in Chemistry and Physics from Alcorn State University. She participated in the NIH funded Alcorn State to Penn State Bridges to the Doctorate Program where she obtained her M.S. degree in Biological Sciences, and then completed her PhD in biochemistry, microbiology and molecular biology at the Pennsylvania State University.

Melanie was recognized as a Rising Star on the CellPress list of Top 100 Inspiring Black Scientists in America and aims to inspire the next generation of scientists to trust that all things will work together for those who believe. Melanie is on the trajectory to establish her independent research group, where her future lab will shed light on metabolic aging and disease. She will return to Penn State as Dorothy Foehr Huck and J. Lloyd Huck Early Career Chair in biochemistry and molecular biology—effective January 2022.

Symposium Title: NAD+ flux is maintained in aged mice

NAD+ is an essential coenzyme found in all living cells. NAD+ concentrations decline during aging, but whether this reflects impaired production or accelerated consumption remains unclear. Here we employed isotope tracing and mass spectrometry to probe NAD+ metabolism across tissues in aged mice. In 25-month-old mice, we observe modest tissue NAD+ depletion (median decrease ~30%) without significant changes in circulating NAD+ precursors. Isotope tracing showed unimpaired synthesis of circulating nicotinamide from tryptophan and maintained flux of circulating nicotinamide into tissue NAD+ pools. Although absolute NAD+ biosynthetic flux was maintained in most tissues of aged mice, fractional tissue NAD+ labeling from infused labeled nicotinamide was modestly accelerated, consistent with increased activity of NAD+ consuming enzymes. Thus, age-related decline in NAD+ is relatively subtle and driven by increased NAD+ consumer activity rather than impaired production.

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scheelinAlexander
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r-gennisRobert
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renskeRenske
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McDonald
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mshen233Mei
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dewoonDavid
Woon
wboulangWilliam
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hy66Hong
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andinomaJosé
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Ray
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egmooreEdwin
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romanovaElena
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roubakhiStanislav
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asoudaAlexander
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trimmellAshley
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Nie
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Han
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Einck
kneef1Kate
Neef
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Xiang
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i-paulIain
Paul
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agerardAnna
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