Professor Stephen Sligar selected for second research collaboration as a Vallee Visiting Professor

Date

08/12/21

Stephen Sligar, a faculty member in the Department of Chemistry, has been selected a Vallee Visiting Professor to pursue collaborative research at the University of Oxford, focusing on protein-protein and protein-lipid recognition events involved in KRas4b cancer signaling.

Sligar was one of the very first Vallee Visiting Professors in 1999. Considered the signature program of the Vallee Foundation, 71 VVPs have been appointed to one-month sabbaticals, traveling to laboratories in Europe, the United States, Australia, Israel, and Singapore.

Recently, the Vallee Foundation offered scientifically active VVPs, with a concrete research collaborative goal, the opportunity to apply for a second, one-month sabbatical. Four scientists, including Sligar, will be heading overseas in the next year or two to further their research and to establish new, or strengthen existing, collaborations.

Sligar will return to the Chemistry Department and Kavli Institute at the University of Oxford, where he will be hosted by Professor Dame Carol Robinson. There, Sligar hopes to explore the application of mass spectrometry to the supramolecular complexes interacting with Nanodiscs, true nanoscale bilayer membranes rendered soluble in aqueous solution by two encircling amphipathic helical protein belts. Of particular interest are the protein-protein and protein-lipid recognition events that are involved in KRas4b cancer signaling.

Sligar’s research focuses on discovering, developing and using chemical and biophysical tools to understand fundamental problems in protein biochemistry and biophysics. His development of nanodisc technology, which are patches of lipid membrane stabilized by a ‘belt’ of membrane scaffolding proteins, has enabled the study of signaling proteins and macromolecular complexes that rely on a membrane. The technology has been used by hundreds of laboratories, benefitting the field of protein science.

Sligar received his PhD in Physics from the University of Illinois in 1975 and returned to the university as a faculty member in 1982 after serving on the faculty in the Department of Molecular Biophysics and Biochemistry at Yale University. He is a previous Director of the School of Chemical Sciences and previous Director of the School of Molecular and Cellular Biology. He is a research professor in the Department of Chemistry, professor in the Center for Biophysics and Quantitative Biology, and a Professor Emeritus in Biochemistry.

Originally named the Bert L & N Kuggie Vallee Foundation Inc., the Boston-based foundation was created in 1996 to promote a collegial community of international scientists, to enhance scientific collaboration and communication, and to advance medical education and biomedical research. This was initially achieved by sponsoring short-term Vallee Visiting Professorships (VVPs) at institutions with which Bert Vallee had developed close collaborations and biennial meetings of this group of biomedical scientists.

 

Related People

s-sligar

Directory

scheelinAlexander
Scheeline
bjmccallBenjamin
McCall
r-gennisRobert
Gennis
j-gerltJohn
Gerlt
sgranickSteve
Granick
mgruebelMartin
Gruebele
hergenroPaul
Hergenrother
huangRaven
Huang
mlkraftMary
Kraft
leckbandDeborah
Leckband
yi-luYi
Lu
martinisSusan
Martinis
snairSatish
Nair
eoldfielEric
Oldfield
cmsCharles
Schroeder
zanZaida
Luthey-Schulten
selvinPaul
Selvin
sksScott
Silverman
s-sligarStephen
Sligar
tajkhorsEmad
Tajkhorshid
zhao5Huimin
Zhao
pbraunPaul
Braun
mdburkeMartin
Burke
jeffchanJefferson
Chan
sdenmarkScott
Denmark
dlottDana
Dlott
foutAlison
Fout
agewirthAndrew
Gewirth
ggirolamGregory
Girolami
sohirataSo
Hirata
jainPrashant
Jain
jkatzeneJohn
Katzenellenbogen
nmakriNancy
Makri
douglasmDouglas
Mitchell
jsmooreJeffrey
Moore
murphycjCatherine
Murphy
r-nuzzoRalph
Nuzzo
dimerPhilip
Phillips
rauchfuzThomas
Rauchfuss
joaquinrJoaquín
Rodríguez-López
sarlahDavid
Sarlah
kschweizKenneth
Schweizer
jsweedleJonathan
Sweedler
vddonkWilfred
van der Donk
renskeRenske
van der Veen
vuraweisJosh
Vura-Weis
mcwhite7M.
White
sczimmerSteven
Zimmerman
beakPeter
Beak
wklemperWalter
Klemperer
jdmcdonaJ.
McDonald
pogoreloTaras
Pogorelov
mshen233Mei
Shen
dewoonDavid
Woon
wboulangWilliam
Boulanger
rxbRohit
Bhargava
qchen20Qian
Chen
jianjuncJianjun
Cheng
hy66Hong
Yang
andinomaJosé
Andino Martinez
decosteDonald
DeCoste
thhuangTina
Huang
tjhummelThomas
Hummel
dkellDavid
Kell
doctorkMichael
Koerner
marvilleKelly
Marville
crrayChristian
Ray
tlbrownTheodore
Brown
rmcoatesRobert
Coates
thdjrThom
Dunning
dykstraClifford
Dykstra
j-jonasJiri
Jonas
j-lisyJames
Lisy
shapleyJohn
Shapley
pshapleyPatricia
Shapley
zumdahl2Steven
Zumdahl
ksuslickKenneth
Suslick
jcoxJenny
Cox
sqdSean
Drummond
sheeleySarah
Sheeley
jsmaddenJoseph
Madden
cknight4Connie
Knight
schulzeHeather
Schulze
kbaumgarKeena
Finney
adkssnBeatrice
Adkisson
trabari1Katie
Trabaris
metclfKara
Metcalf
ljohnso2Lori
Johnson
lchenoweLeslie
Chenoweth
wdedoWolali
Dedo
spinnerDavid
Spinner
plblumPatricia
Simpson
stevens2Chad
Stevens
lsagekarLori
Sage-Karlson
bertholdDeborah
Berthold
kecarlsoKathryn
Carlson
sdesmondSerenity
Desmond
axelson2Jordan
Axelson
scbakerStephanie
Baker
pflotschPriscila
Falagan Lotsch
dgrayDanielle
Gray
thennes2Tom
Hennessey
holdaNancy
Holda
aibarrAlejandro
Ibarra
kimshSung Hoon
Kim
kocherg2Nikolai
Kocherginsky
philipk2Philip
Kocheril
legare2Stephanie
Legare
alewandoAgnieszka
Lewandowska
smccombiStuart
McCombie
jdm5Justin
McGlauchlen
egmooreEdwin
Moore
myerscouKathleen
Myerscough
snalla2Siva
Nalla
romanovaElena
Romanova
roubakhiStanislav
Rubakhin
shvedalxAlexander
Shved
asoudaAlexander
Soudakov
xywangXiying
Wang
kwilhelKaren
Wilhelmsen
wilkeyRandy
Wilkey
silongSilong
Zhang
schlembaMary
Schlembach
trimmellAshley
Trimmell
emccarr2Elise
McCarren
cmercierChristen
Mercier
atimpermAaron
Timperman
niesShuming
Nie
hshanHee-Sun
Han
mmgMutha
Gunasekera
kknightsKatriena
Knights
lisawLisa
Williamson
keinckKatie
Einck
kneef1Kate
Neef
txiang4Tiange
Xiang
j-hummelJohn
Hummel
i-paulIain
Paul
munjanjaLloyd
Munjanja
glnGayle
Nelsen
agerardAnna
Gerard
powerskaKimberly
Powers
lolshansLisa
Olshansky
miricaLiviu
Mirica
qingcao2Qing
Cao
lisa3Lisa
Johnson
tinalambTina
Lamb
baronpBaron
Peters
bransle2Sarah
Bransley
dylanmh2Dylan
Hamilton
raegansRaegan
Smith
apm8Angad
Mehta
leverittJohn
Leveritt
xingwXing
Wang
emillrEva
Miller
jmill24Jacqueline
Miller
jlbass2Julia
Bass
ramonarRamona
Rudzinski
tlcraneTracy
Crane
cejohnstCelia
Johnston
adlAmber
LaBau
cnsolomoCandice
Solomon-Strutz
mikaelbMikael
Backlund
jacksonnNick
Jackson