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David Sarlah

Profile picture for David Sarlah

Contact Information

Department of Chemistry
University of Illinois
270 RAL, Box 107-5
600 South Mathews Avenue
Urbana, IL 61801

Research Areas

Associate Professor of Chemistry

Biography

Professor Sarlah received his undergraduate degree in chemistry from the University of Ljubljana in 2006 and his Ph.D. from the Scripps Research Institute in 2011. Following a postdoctoral stay at ETH Zürich, he joined the faculty at Illinois in 2014. His research interests span from the synthesis of complex, biologically active natural products and the related chemical biology to methodology development.

Research Interests

synthesis of natural products and the related chemical biology; methodology development; asymmetric catalysis

Research Description

Central to our research program is the advancement of the science of synthesis. We are involved in natural products chemistry and synthesis, reaction innovation and design including asymmetric catalysis. We aim to provide new solutions to the problems encountered at the frontline of organic synthesis that benefit chemistry and enable advances in the allied fields of chemical biology, material science, and medicine.

Awards and Honors

2021 Arthur C. Cope Scholar Award

2020 KYOTO Rising-Star Lectureship Award

2020 FMC New Investigator Award

American Cancer Society Research Scholar, 2020-2024

2019 Eli Lilly Grantee Award

2019 Amgen Young Investigator Award

2019 BMS Unrestricted Grant Award in Synthetic Chemistry

2019 Grammaticakis-Neumann Award

2017 Lincoln Excellence for Assistant Professors Scholar by the College of LAS

2017 Alfred P. Sloan Research Fellow

2017 NSF CAREER Award

 

Additional Campus Affiliations

Associate Professor, Chemistry
Associate Professor, Carl R. Woese Institute for Genomic Biology

Honors & Awards

2021 Arthur C. Cope Scholar Award

2020 KYOTO Rising-Star Lectureship Award

2020 FMC New Investigator Award

American Cancer Society Research Scholar, 2020-2024

2019 Eli Lilly Grantee Award

2019 Amgen Young Investigator Award

2019 BMS Unrestricted Grant Award in Synthetic Chemistry

2019 Grammaticakis-Neumann Award

2017 Lincoln Excellence for Assistant Professors Scholar by the College of LAS

2017 Alfred P. Sloan Research Fellow

2017 NSF CAREER Award

 

Recent Publications

Angelini, E., Martinelli, M., Roà, E., Ungarean, C. N., Salome, C., Lefebvre, Q., Bournez, C., Fessard, T. C., & Sarlah, D. (2024). Diversification of Simple Arenes into Complex (Amino)cyclitols. Chemistry - A European Journal, 30(6), Article e202303262. https://doi.org/10.1002/chem.202303262

Davis, C. W., Zhang, Y., Li, Y., Martinelli, M., Zhang, J., Ungarean, C., Galer, P., Liu, P., & Sarlah, D. (2024). Copper-Catalyzed Dearomative 1,2-Hydroamination. Angewandte Chemie International Edition, Article e202407281. Advance online publication. https://doi.org/10.1002/anie.202407281

Roy, P., Maturano, J., Hasdemir, H., Lopez, A., Xu, F., Hellman, J., Tajkhorshid, E., Sarlah, D., & Das, A. (2024). Elucidating the Mechanism of Metabolism of Cannabichromene by Human Cytochrome P450s. Journal of Natural Products, 87(4), 639-651. https://doi.org/10.1021/acs.jnatprod.3c00336

Siddiqi, Z., Bingham, T. W., Shimakawa, T., Hesp, K. D., Shavnya, A., & Sarlah, D. (2024). Oxidative Dearomatization of Pyridines. Journal of the American Chemical Society, 146(4), 2358-2363. https://doi.org/10.1021/jacs.3c13603

Matsuoka, W., Kawahara, K. P., Ito, H., Sarlah, D., & Itami, K. (2023). π-Extended Rubrenes via Dearomative Annulative π-Extension Reaction. Journal of the American Chemical Society, 145(1), 658-666. https://doi.org/10.1021/jacs.2c11338

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