PROFESSORINTERESTS
Martin D. BurkeSynthesis and study of small molecules with protein-like functions; molecular prosthetics; synthesis of complex natural products; iterative cross-coupling; MIDA boronates
Jefferson ChanSynthesis of activity-based sensing probes for point-of-care diagnostic applications; development of chemically responsive platforms for on-demand and site-selective drug delivery; rationale design of therapeutic agents for neurological disorders and cancer
Scott E. DenmarkThe invention, development, and application of catalytic asymmetric organic reactions; elucidation of structure-reactivity relationships employing spectroscopic, crystallographic, and computational methods; application of AI/machine learning to accelerate optimization of catalysts and reaction conditions    
Paul J. HergenrotherUsing compounds derived from synthetic organic chemistry and natural products to explore biological systems; examples include the synthesis and evaluation of anticancer and antibacterial agents with novel modes of action   
Mayuko IsomuraMethodology development; asymmetric catalysis; discovery of novel reactivities and practical synthetic methods by developing new catalysts and understanding reaction mechanisms
Joomyung (Vicky) JunSynthesis of small-molecule chemical tools (i) to reversibly esterify proteins for in vivo protein-based drug delivery, (ii) to develop fluorogenic sensors to investigate the cellular uptake mechanism of biologics, and (iii) to devise trifunctional activity-based probes for molecular imaging and new target discovery
Angad P. MehtaSynthetic chemistry and synthetic biology: (i) to combat emerging viral pathogens and drug-resistant bacteria; (ii) for directed endosymbiosis (an engineered, symbiotic cell within a host cell) to develop platforms for evolutionary studies and photosynthetic biosynthesis; and (iii) for engineering selectivity in targeting cancer
Liviu M. MiricaTransition metal-catalyzed C–H bond activation and C–C/C–heteroatom bond formation reactions; organic transformations promoted by single electron transfer (SET) processes; photoredox catalysis and electrocatalysis
Scott K. SilvermanDNA as a catalyst
Wilfred A. van der DonkUse of synthetic organic chemistry to address biological problems; antibiotic synthesis is of particular interest  
M. Christina WhiteSynthesis-driven reaction discovery dedicated to the discovery and study of practical, selective catalytic reactions that streamline the synthesis and late-stage functionalization of complex molecules; examples include site-selective C–H hydroxylations and aminations and asymmetric C–H oxidations and alkylations

 

Other Faculty with Interests in Organic Chemistry:

PROFESSORINTERESTS
Gregory S. GirolamiOrganometallic chemistry; catalysis
Mary L. Kraft (faculty affiliate)Biomembrane surface science
Samy Meroueh (faculty affiliate)Bioorganic and medicinal chemistry
Jeffrey S. Moore (research faculty)Self-healing polymers; mechanochemistry; nanostructures
Ralph G. Nuzzo (research faculty)Functional organic materials 
Eric OldfieldAntibiotics; anti-cancer drugs
Lisa OlshanskySynthesis and application of switchable ligands to support dual metal ion coordination geometries 
Huimin Zhao (faculty affiliate)Natural product biosynthesis; synthetic biology