| PROFESSOR | INTERESTS |
|---|---|
| Martin D. Burke | Synthesis and study of small molecules with protein-like functions; molecular prosthetics; synthesis of complex natural products; iterative cross-coupling; MIDA boronates |
| Jefferson Chan | Synthesis of activity-based sensing probes for point-of-care diagnostic applications; development of chemically responsive platforms for on-demand and site-selective drug delivery; rationale design of therapeutic agents for neurological disorders and cancer |
| Scott E. Denmark | The invention, development, and application of catalytic asymmetric organic reactions; elucidation of structure-reactivity relationships employing spectroscopic, crystallographic, and computational methods; application of AI/machine learning to accelerate optimization of catalysts and reaction conditions |
| Paul J. Hergenrother | Using compounds derived from synthetic organic chemistry and natural products to explore biological systems; examples include the synthesis and evaluation of anticancer and antibacterial agents with novel modes of action |
| Mayuko Isomura | Methodology development; asymmetric catalysis; discovery of novel reactivities and practical synthetic methods by developing new catalysts and understanding reaction mechanisms |
| Joomyung (Vicky) Jun | Synthesis of small-molecule chemical tools (i) to reversibly esterify proteins for in vivo protein-based drug delivery, (ii) to develop fluorogenic sensors to investigate the cellular uptake mechanism of biologics, and (iii) to devise trifunctional activity-based probes for molecular imaging and new target discovery |
| Angad P. Mehta | Synthetic chemistry and synthetic biology: (i) to combat emerging viral pathogens and drug-resistant bacteria; (ii) for directed endosymbiosis (an engineered, symbiotic cell within a host cell) to develop platforms for evolutionary studies and photosynthetic biosynthesis; and (iii) for engineering selectivity in targeting cancer |
| Liviu M. Mirica |
Transition metal-catalyzed C–H bond activation and C–C/C–heteroatom bond formation reactions; organic transformations promoted by single electron transfer (SET) processes; photoredox catalysis and electrocatalysis |
| Scott K. Silverman | DNA as a catalyst |
| Wilfred A. van der Donk | Use of synthetic organic chemistry to address biological problems; antibiotic synthesis is of particular interest |
| M. Christina White | Synthesis-driven reaction discovery dedicated to the discovery and study of practical, selective catalytic reactions that streamline the synthesis and late-stage functionalization of complex molecules; examples include site-selective C–H hydroxylations and aminations and asymmetric C–H oxidations and alkylations |
Other Faculty with Interests in Organic Chemistry:
| PROFESSOR | INTERESTS |
|---|---|
| Gregory S. Girolami | Organometallic chemistry; catalysis |
| Mary L. Kraft (faculty affiliate) | Biomembrane surface science |
| Samy Meroueh (faculty affiliate) | Bioorganic and medicinal chemistry |
| Jeffrey S. Moore (research faculty) | Self-healing polymers; mechanochemistry; nanostructures |
| Ralph G. Nuzzo (research faculty) | Functional organic materials |
| Eric Oldfield | Antibiotics; anti-cancer drugs |
| Lisa Olshansky | Synthesis and application of switchable ligands to support dual metal ion coordination geometries |
| Huimin Zhao (faculty affiliate) | Natural product biosynthesis; synthetic biology |